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Publications: Fact Sheets and More

Hepatitis: A Summary of NIH-Funded Research

April 7, 2012 • Posted in Fact Sheets and More

The 2008 research protocols listed below include studies that conduct invasive research on whole, living chimpanzees as well as those that use biological samples from chimpanzees (i.e. cells, tissues, blood, and/or serum.)

Researcher: ALTER, HARVEY J.
Grant No. 1Z01CL002082-1308
Project: Studies of Viral Hepatitis and AIDS in the Chimpanzee Model
Institution: NIH/Intramural
Project runs: Grant first appeared in 1996; renewed yearly
Funding: Unavailable

 

Researcher: ALLEN, TODD M
Grant No. 5U19AI066345-040005
Project: CD8 T Cell Selective Pressure and Hepatitis C Virus Sequence Evolution
Institution: MASSACHUSETTS GENERAL HOSPITAL
Project runs: Unavailable
Funding: Unavailable

 

Researcher: ALLEN, TODD M
Grant No. 5R01AI067926-03
Project: CD8 T Cell Selective Pressure and HCV Sequence Evolution
Institution: MASSACHUSETTS GENERAL HOSPITAL
Project runs: Aug. 15, 2006 – July 31, 2010
Funding: $517,856 ($169,784 for 2008)

 

Researcher: RITOLA, KIMBERLY D.
Grant No. 5F32DK080650-02
Project: Viral Dynamics of HCV Serine Protease Inhibitor Resistance
Institution: ROCKEFELLER UNIVERSITY
Project runs: Sept. 1, 2007 – Aug. 31, 2010
Funding: $100,924 ($51,278 for 2008)

 

Researcher: LIANG, T. JAKE
Grant No. 1Z01DK054504-1208
Project: Animal And Culture Models of Viral Hepatitis And Hepatocellular Carcinoma
Institution: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: LANFORD, ROBERT E.
Grant No. 5R21AI067455-02
Project: Resolution of Acute Hepatitis B Virus Infections in Chimpanzees
Institution: SOUTHWEST FOUNDATION FOR BIOMEDICAL RES
Project runs: Mar. 1, 2007 – Feb. 28, 2010
Funding: $448,519 ($222,579 for 2008)

 

Researcher: PURCELL, ROBERT H.
Grant No. 1Z01AI001015-0208
Project: Pathogenesis of Parenteral Viral Hepatitis
Institution: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: PURCELL, ROBERT H.
Grant No. 1Z01AI001016-0208
Project: New Approaches To Passive Immunoprophylaxis
Institution: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: PURCELL, ROBERT H.
Grant No. 1Z01AI000823-1108
Project: New Approaches To Active Immunoprophylaxis
Institution: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: REHERMANN, BARBARA
Grant No. 1Z01DK054508-1108
Project: Analysis and Modulation of Virus-Host Interaction in Animal Models
Institution: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: GRAKOUI, ARASH
Grant No. 5R01AI070101-03
Project: Mechanisms of hepatitis C virus persistence
Institution: EMORY UNIVERSITY
Project runs: Sept. 1, 2006 – Aug. 31, 2011
Funding: $401,835

 

Researcher: PURCELL, ROBERT H.
Grant No. 1Z01AI000311-2708
Project: Search For New and Emerging Etiologic Agents
Institution: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: WALKER, CHRISTOPHER M.
Grant No. 5U19AI048231-090001
Project: HCV-Specific Cellular Immunity in Acute Hepatitis C
Institution: RESEARCH INST NATIONWIDE CHILDREN’S HOSPITAL - COLUMBUS, OH
Project runs: Unavailable
Funding: Unavailable

 

Researcher: BHARDWAJ, NINA
Grant No. 5R01AI061684-05
Project: Dendritic Cell mediated induction of Anti-HCV immunity
Institution: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
Project runs: July 1, 2004 – June 30, 2009
Funding: $571,176

 

Researcher: WALKER, CHRISTOPHER M
Grant No. 5R37AI047367-09
Project: HCV-specific T cell response
Institution: RESEARCH INST NATIONWIDE CHILDREN’S HOSPITAL
Project runs: Aug. 15, 1999 – Dec. 31, 2009
Funding: $541,702

 

Researcher: GALE, MICHAEL J.
Grant No. 5U19AI040035-130004
Project: Innate Defenses that Control Hepatitis C Virus (HCV)
Institution: UNIVERSITY OF TEXAS MEDICAL BR GALVESTON
Project runs: Unavailable
Funding: Unavailable

 

Researcher: LANFORD, ROBERT E.
Grant No. 5U19AI040035-130002
Project: Virus-Host Interactions in Hepatitis C Virus (HCV) Infections
Institution: UNIVERSITY OF TEXAS MEDICAL BR GALVESTON
Project runs: Unavailable
Funding: Unavailable

 

Researcher: RICE, CHARLES M.
Grant No. 5U19AI040034-14
Project: Hepatitis C: Studies of Immunity and Pathogenesis
Institution: ROCKEFELLER UNIVERSITY
Project runs: Aug. 1, 1997 – June 30, 2010
Funding: $797,618

 

Researcher: WALKER, CHRISTOPHER M
Grant No. 5U19AI048231-09
Project: HCV Replication and Immunity
Institution: RESEARCH INST NATIONWIDE CHILDREN’S HOSPITAL
Project runs: July 14, 2005 – June 30, 2010
Funding: $918,189

 

Researcher: LIANG, T. JAKE
Grant No. 1Z01DK054503-1208
Project: Molecular Approaches To Vaccine Development For Hepatitis C
Institution: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: LIANG, T. JAKE
Grant No. 1Z01DK054505-1208
Project: Mechanisms of Interferon Action and Resistance in Hepatitis C Virus Infection
Institution: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: ARNTZEN, CHARLES J
Grant No. 5U19AI066332-04
Project: Plant-derived vaccines against hepatitis C Cooperative
Institution: ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
Project runs: Aug. 1, 2005 – July 31, 2010
Funding: $714,512

(The above project may involve primates other than chimpanzees.)

Researcher: CHISARI, FRANCIS V.
Grant No. 2R01AI020001-25
Project: Pathogenesis of Liver Disease in Hepatitis
Institution: SCRIPPS RESEARCH INSTITUTE - CA
Project runs: July 1, 1983 – Dec. 31, 2012
Funding: $685,357

 

Researcher: DUBENSKY, THOMAS W
Grant No. 5U01AI070834-04
Project: Development of Listeria-Based Clinical Consensus HCV Vaccine Candidates
Institution: DUBENSKY, THOMAS W
Project runs: Aug. 1, 2006 – July 31, 2009
Funding: $354,663

 

Researcher: EMERSON, SUZANNE U.
Grant No. 1Z01AI000970-0308
Project: Molecular Studies of Hepatitis C Virus.
Institution: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: EXLEY, MARK A
Grant No. 5R01DK066917-05
Project: Innate-like hepatic CD1d-reative NKT cells: Liver Disease
Institution: BETH ISRAEL DEACONESS MEDICAL CENTER
Project runs: Sept. 1, 2004 – July 31, 2009
Funding: $197,460

 

Researcher: FLOTTE, TERENCE R
Grant No. 5P01DK058327-090002
Project: Liver-directed Gene Therapy for Alpha 1 Antitrypsin (AAT) Deficiency
Institution: UNIVERSITY OF FLORIDA
Project runs: Unavailable
Funding: Unavailable

 

Researcher: JONES, CHRISTOPHER T
Grant No. 5F32DK081193-02
Project: Characterization of the HCV p7 Protein
Institution: ROCKEFELLER UNIVERSITY
Project runs: Sept. 3, 2007 – Sept. 2, 2010
Funding: $52,898

 

Researcher: LEMON, STANLEY M
Grant No. 5U19AI040035-13
Project: The Southeastern Cooperative Hepatitis C Research Group
Institution: UNIVERSITY OF TEXAS MEDICAL BR GALVESTON
Project runs: Aug. 1, 1997 – June 30, 2010
Funding: $1,414,039

 

Researcher: PURCELL, ROBERT H.
Grant No. 1Z01AI000915-0708
Project: Pathogenesis Of Enteric Viral Hepatitis
Institution: NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Project runs: Unavailable
Funding: Unavailable

 

Researcher: ALTER, HARVEY
Grant No. 1Z01CL002076-1308
Project: Evaluation Of Nucleic Acid Vaccine As A Preventive And Therapeutic Modality
Institution: NIH (CLINICAL CENTER)
Project runs: Unavailable
Funding: Unavailable

 

Researcher: NICOSIA, ALFREDO
Grant No. 5U01AI070802-03
Project: Development of an Adenovirus based HCV Vaccine: preclinical safety and immunology
Institution: OKAIROS, POMEZIA (RM) - Italy
Project runs: Sept. 1, 2006 – Aug. 31, 2009
Funding: $180,033

 

Researcher: CHISARI, FRANCIS
Grant No. 2R01CA076403-06A1
Project: Hepatitis C Virus Immunobiology and Pathogenesis
Institution: Scripps Research Institute, La Jolla, CA
Project runs: December 12, 1997 - May 31, 2008
Funding: $544,625

 

Researcher: CHISARI, FRANCIS
Grant No. 1R01CA108304-01
Project: Cellular Genes that Control HCV Replication
Institution: Scripps Research Institute, La Jolla, CA
Project runs: December 19, 2003 - August 31, 2008
Funding: $403,153

 

Researcher: WALKER, CHRISTOPHER
Grant No. 5R01AI060388-02
Project: AAV vectors for prevention and therapy of HCV infection
Institution: Children’s Research Institute, Columbus, OH
Project runs: September 29, 2003 - September 28, 2008
Funding: $408,128

 


Sources

Grant information is from the NIH Computer Retrieval of Information on Scientific Projects (CRISP) database and funding amounts, when available, are obtained from the National Institutes of Health Research Portfolio Online Reporting Tool.

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